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DFI

Best DFI Treatment In India

Related By Fertility

The Sperm DNA Fragmentation Index (DFI) measures the damage to the DNA, the sperm's genetic material. Infertility is scientifically defined as a lack of pregnancy after 12 months of unprotected sexual intercourse. Infertility affects 10-15% of the global population, and its prevalence has been rising in recent years. Male factors are involved in around 50% of cases of infertility, with 20% cases of pure "male factor" infertility and 30% cases of mixed female and male factor infertility. Traditional semen analysis is now utilised to evaluate and diagnose male infertility, including the volume, concentration, vitality, and morphology of the semen. Infertility affects around 15% of males with normal sperm analyses. As a result, sperm analysis alone can only provide limited information for measuring male viability and does not provide a full picture. indicate the capacity of the sperm to fertilise Conventional sperm analysis has fallen short of expectations.

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DFI

Describe DFI.

DFI (DNA Fragmentation Index) is a measure of degree of DNA damage in a sample, typically sperm cells.
It is an essential tool for identifying possible sperm damage and assessing the quality of semen.

Male reproductive potential and embryo development have been found to be impacted by the presence of fragmented DNA in sperm. It may also contribute to unsuccessful IVF attempts and repeated miscarriages.

Men with advanced age, varicocele and external genital irritation, bad lifestyle choices including smoking and drinking, and exposure to radiation and pollution are more likely to have high DFI levels.



DFI

Benefits & Losses

Benefits:
  • This process enables us to determine whether or not the male partner's semen sample may be used. We advise using a sperm donor if the degree of fragmentation is greater.
Dangers:
  • The health of the male partner is unaffected by the risks associated with sperm DNA fragmentation. The method does appear to have certain limits, though.

DFI

Diagnosis

This treatment aids in the diagnosis of male infertility, particularly when:

  • Couples with a history of poor or halted embryonic development;
  • Unexplained infertility;
  • Several failed ART cycles;
  • Recurrent miscarriages;
  • Older males;
  • Varicocele;
  • Abnormal semen analysis;
  • And exposure to dangerous chemicals such as smoke, alcohol, radiation, etc.

The DNA fragmentation index of sperm (DFI) is measured using a simple procedure, similar to a standard semen assessment.

Semen acquisition:
  • A sample of the male's sperm is taken for analysis.

Sperm analysis:
  • To assess the degree of sperm DNA fragmentation, our specialists perform a number of diagnostic procedures.

DFI

From Doctor's end

Most fertility specialists do not advise this testing as a primary course of therapy, although they do acknowledge its use in

The following situations:

  • After unsuccessful attempts at assisted reproduction
  • (ICSI, IUI, or IVF)
  • Clinical varicocele present
  • Smokers
  • Multiple genital infections
  • Unaccounted-for infertility
  • Older than 40
  • Multiple miscarriages (at least 2)
  • Exposure of people to harmful chemical substances
  • Radiotherapy or chemotherapy use in the past

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